World Wide Mutant
Summary Mutant for Explorer
Information about nsp10
Description
The NSP10 stimulates both NSP14 3'-5' exoribonuclease and NSP16 2?-O-ribose methyltransferase activities as a cofactor. Therefore plays an essential role in viral RNAs capping methylation. This camouflages the viral RNA from the host's innate immune system and degradation by 5?-3?exoribonucleases.
SequenceAGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQ
Length and Mass139 aa; 150 kDa
