World Wide Mutant

Summary Mutant for Explorer

Information about nsp10

Description

The NSP10 stimulates both NSP14 3'-5' exoribonuclease and NSP16 2?-O-ribose methyltransferase activities as a cofactor. Therefore plays an essential role in viral RNAs capping methylation. This camouflages the viral RNA from the host's innate immune system and degradation by 5?-3?exoribonucleases.

Sequence

AGNATEVPANSTVLSFCAFAVDAAKAYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDHPNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQ

Length and Mass

139 aa; 150 kDa

Pie chart